Article
Docking and rolling, a model of how the mitotic motor Eg5 works.
The Journal of biological chemistry - 21 Oct 2005
Rosenfeld Steven S, Xing Jun, Jefferson Geraldine M, King Peter H
Abstract excerpt
Whereas kinesin I is designed to transport cargoes long distances in isolation, a closely related kinesin motor, Eg5, is designed to generate a sustained opposing force necessary for proper mitotic spindle formation. Do the very different roles for these evolutionarily related motors translate into differences in how they generate movement? We have addressed this question by examining when in the ATPase cycle the...
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