Article
The Effect of Sex-Specific Differences on IL-10-/- Mouse Colitis Phenotype and Microbiota.
International journal of molecular sciences - 20 Jun 2023
Maite Casado-Bedmar, Roy Maryline, Emilie Viennois
Abstract excerpt
Sexual dimorphism is an important factor in understanding various diseases, including inflammatory bowel disease (IBD). While females typically exhibit stronger immune responses, the role of sex in IBD remains unclear. This study aimed to explore the sex-dependent differences and inflammatory susceptibility in the most extensively used IBD mouse model as they developed colitis. We monitored IL10-deficient mice...
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