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Article

Ethnic differences in CYP2C92 (Arg144Cys) and CYP2C93 (Ile359Leu) genotypes in Japanese and Israeli populations.

Life sciences - 19 Nov 2005

Nakai Kenji, Habano Wataru, Nakai Keiko, Fukushima Noriko, Suwabe Akira, Moriya Shogo, Osano Kaoru, Gurwitz David

Abstract excerpt

CYP2C9 is a major P450 2C enzyme, which hydroxylates about 16% of drugs that are in current clinical use and contributes to the metabolism of a number of clinically important substrate drugs such as warfarin. Ethnic differences in the genetic variation of CYP2C9 have been reported, and might be related to the frequencies of adverse reactions to drugs metabolized by CYP2C9 in different ethnic groups. In the...

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Identifiers

PMID: 16111713
DOI: 10.1016/j.lfs.2005.04.049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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