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Article

Analysis of CYP2C92, CYP2C93 and VKORC1 -1639 G>A polymorphisms in a population from South-Eastern Europe.

Journal of cellular and molecular medicine - 1 Dec 2012

Buzoianu Anca D, Trifa Adrian P, Mureşanu Dafin F, Crişan Sorin

Abstract excerpt

The CYP2C9 enzyme metabolizes a wide range of relevant drugs, among which are oral anticoagulants. VKORC1 is the pharmacodynamic target of the oral anticoagulants. The genetic polymorphisms CYP2C9*2, CYP2C9*3 and VKORC1 -1639 G>A are the major determinants of the inter-individual variability in the dosage requirements of oral anticoagulants. This study provides a first evaluation of these 3 polymorphisms in a...

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Source

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Identifiers

PMID: 22863573
DOI: 10.1111/j.1582-4934.2012.01606.x
PMCID: PMC4393720

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Analysis of CYP2C9*2, CYP2C9*3 and VKORC1 -1639 G>A polymorphisms in a population from South-Eastern Europe.PMID 22863573Read ↗

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