Article
von Willebrand factor: two sides of a coin.
Journal of thrombosis and haemostasis : JTH - 1 Aug 2005
Sadler J E
Abstract excerpt
Everyone experiences minor bleeding and clotting, and many illnesses feature extremes of hemorrhage or thrombosis. Recent advances have illuminated the ways in which von Willebrand factor (VWF) contributes to both kinds of hemostatic emergency, whether mundane or life threatening, often through disturbances in VWF synthesis or catabolism. von Willebrand factor multimer assembly depends on the ability of the...
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