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Article

Detection and clinical implications of early systemic tumor cell dissemination in breast cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Dec 2003

Pantel Klaus, Müller Volkmar, Auer Margherita, Nusser Nathalie, Harbeck Nadia, Braun Stephan

Abstract excerpt

Blood-borne distant metastasis is the leading cause of cancer-related death in breast cancer. The onset of this fundamental process can now be assessed in cancer patients using ultrasensitive immunocytochemical and molecular assays able to detect even single metastatic cells. Analyses of bone marrow (BM) samples show that disseminated cells are present in 20-40% of primary breast cancer patients without any...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 14695131

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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