Article
A comparison of glutathione S-transferase mutant frequencies in healthy Han and Uygur Chinese.
European journal of drug metabolism and pharmacokinetics - 1 Jan 2000
Zhong Shi-Long, Zhou Shufeng, Huang Min
Abstract excerpt
OBJECTIVE: This study was to compare the frequencies of genetic polymorphisms of GSTM1, GSTT1, and GSTP1 in Uygur Chinese with those in Han Chinese. METHODS: GSTM1 and GSTT1 polymorphisms were analyzed by a PCR-Multiplex procedure, whereas GSTP1 polymorphism was analyzed by PCR-RFLP. RESULTS: The frequency of GSTM1 null genotype in Han Chinese (56.1%) was similar to that in Uygur Chinese (53.2%) (P = 0.592),...
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