Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Carbohydrate composition of meningococcal lipopolysaccharide modulates the interaction of Neisseria meningitidis with human dendritic cells.

Cellular microbiology - 1 Sept 2005

Kurzai Oliver, Schmitt Corinna, Claus Heike, Vogel Ulrich, Frosch Matthias, Kolb-Mäurer Annette

Abstract excerpt

Meningococcal lipopolysaccharide (LPS) is of crucial importance for the pathogenesis of invasive infection. We show that sialylation and elongation of the alpha-chain effectively shields viable unencapsulated Neisseria meningitidis from recognition by human dendritic cells (DC). In contrast, beta- and gamma- chain of the LPS carbohydrate moiety play only a minor role in the interaction with DC. The protective...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Capsules
Share to Glycosyltransferases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microscopy, Electron, Transmission

Share to N-Acetylglucosaminyltransferases

Share to Neisseria meningitidis

Share to Neisseria meningitidis, Serogroup B

Share to Phagocytosis

Share to Scavenger Receptors, Class A

Source

Identifiers

PMID: 16098219
DOI: 10.1111/j.1462-5822.2005.00559.x

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Carbohydrate composition of meningococcal lipopolysaccharide modulates the interaction of Neisseria meningitidis with human dendritic cells.PMID 16098219Read ↗

Activation of human dendritic cells is modulated by components of the outer membranes of Neisseria meningitidis.Semantic proximity Read ↗

Neisseria meningitidis expressing lgtB lipopolysaccharide targets DC-SIGN and modulates dendritic cell function.Semantic proximity Read ↗

Lipopolysaccharide engineering in Neisseria meningitidis: structural analysis of different pentaacyl lipid A mutants and comparison of their modified agonist properties.Semantic proximity Read ↗

How the Knowledge of Interactions between Meningococcus and the Human Immune System Has Been Used to Prepare Effective<i>Neisseria meningitidis</i>VaccinesSemantic proximity Read ↗

Lipooligosaccharide Structures of Invasive and Carrier Isolates of Neisseria meningitidis Are Correlated with Pathogenicity and CarriageSemantic proximity Read ↗

Variation of Neisseria gonorrhoeae lipooligosaccharide directs dendritic cell-induced T helper responses.Semantic proximity Read ↗

Adjuvant effects elicited by novel oligosaccharide variants of detoxified meningococcal lipopolysaccharides on Neisseria meningitidis recombinant PorA protein: a comparison in mice.Semantic proximity Read ↗

Survival and evasion of Neisseria meningitidis from macrophagesSemantic proximity Read ↗

Activation of human meningeal cells is modulated by lipopolysaccharide (LPS) and non-LPS components of Neisseria meningitidis and is independent of Toll-like receptor (TLR)4 and TLR2 signalling.Semantic proximity Read ↗

Attachment and invasion of Neisseria meningitidis to host cells is related to surface hydrophobicity, bacterial cell size and capsule.Semantic proximity Read ↗

Lessons from an LPS-deficient Neisseria meningitidis mutant.Semantic proximity Read ↗

Carbohydrate based meningococcal vaccines: past and present overviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.