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Article

Normal and leukaemic stem cells.

British journal of haematology - 1 Aug 2005

Bonnet Dominique

Abstract excerpt

The blood-related cancer leukaemias were the first diseases where human cancer stem cells, or leukaemic stem cells (LSC), were isolated. The haematopoietic system is one of the best tissues for investigating cancer stem cells, because the developmental hierarchy of normal blood formation is well defined. Leukaemias can now be viewed as aberrant haematopoietic processes initiated by rare LSC that have maintained...

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Identifiers

PMID: 16098060
DOI: 10.1111/j.1365-2141.2005.05596.x

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