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Immunophenotypic features of early haematopoietic and leukaemia stem cells

24 Jul 2024

Abstract excerpt

Many tumours are organised in a hierarchical structure with at its apex a cell that can maintain, establish, and repopulate the tumour-the cancer stem cell. The haematopoietic stem cell (HSC) is the founder cell for all functional blood cells. Like HSCs, the leukaemia stem cells (LSC) are hypothesised to be the leukaemia-initiating cells, which have features of stemness such as self-renewal, quiescence, and...

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PMID: 39045906
DOI: 10.1111/ijlh.14348

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