Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of JAK/STAT signalling components by genome-wide RNA interference.

Nature - 11 Aug 2005

Müller Patrick, Kuttenkeuler David, Gesellchen Viola, Zeidler Martin P, Boutros Michael

Abstract excerpt

Signalling pathways mediating the transduction of information between cells are essential for development, cellular differentiation and homeostasis. Their dysregulation is also frequently associated with human malignancies. The Janus tyrosine kinase/signal transducer and activator of transcription (JAK/STAT) pathway represents one such signalling cascade whose evolutionarily conserved roles include cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epistasis, Genetic
Share to Hemocytes
Share to JNK Mitogen-Activated Protein Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Tyrosine Phosphatases

Share to Protein Tyrosine Phosphatases, Non-Receptor

Share to RNA Interference

Share to STAT1 Transcription Factor

Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 16094372
DOI: 10.1038/nature03869

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of JAK/STAT signalling components by genome-wide RNA interference.PMID 16094372Read ↗

Drosophila Jak/STAT Signaling: Regulation and Relevance in Human Cancer and MetastasisSemantic proximity Read ↗

The Functions of BET Proteins in Gene Transcription of Biology and DiseasesSemantic proximity Read ↗

Epigenetic gene regulation by Janus kinase 1 in diffuse large B-cell lymphomaSemantic proximity Read ↗

In vivo identification of novel STAT5 target genesSemantic proximity Read ↗

Bromodomain and extra-terminal (BET) family proteins: New therapeutic targets in major diseasesSemantic proximity Read ↗

The Drosophila homolog of the human tumor suppressor gene BHD interacts with the JAK-STAT and Dpp signaling pathways in regulating male germline stem cell maintenanceSemantic proximity Read ↗

Functional genomic analysis of the Wnt-wingless signaling pathway.Semantic proximity Read ↗

Biological and clinical significance of the JAK-STAT pathway; lessons from knockout miceSemantic proximity Read ↗

BET family members Bdf1/2 modulate global transcription initiation and elongation in <i>Saccharomyces cerevisiae</i>Semantic proximity Read ↗

Identification of the BRD1 interaction network and its impact on mental disorder risk.Semantic proximity Read ↗

Biology and significance of the JAK/STAT signalling pathways.Semantic proximity Read ↗

Interactome Rewiring Following Pharmacological Targeting of BET BromodomainsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.