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Article

The cellular mRNA expression of GABA and glutamate receptors in spinal motor neurons of SOD1 mice.

Journal of the neurological sciences - 15 Nov 2005

Petri S, Schmalbach S, Grosskreutz J, Krampfl K, Grothe C, Dengler R, Van Den Bosch L, Robberecht W, Bufler J

Abstract excerpt

ALS is a fatal neurodegenerative disorder characterized by a selective loss of upper motor neurons in the motor cortex and lower motor neurons in the brain stem and spinal cord. About 10% of ALS cases are familial, in 10-20% of these, mutations in the gene coding for superoxide dismutase 1 (SOD1) can be detected. Overexpression of mutated SOD1 in mice created animal models which clinically resemble ALS....

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Source

Identifiers

PMID: 16087196
DOI: 10.1016/j.jns.2005.06.005

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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