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Sequence analysis of the mitochondrial genome from a large family with maternally inherited nonsyndromic deafness.

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Aug 2005

Zhang Hai-jun, Xu Chun-hong, Zhan Yi-ju, Zhao Su-ying, Shan Yun-feng, Geng Xue-xia, Shan Xiang-nian

Abstract excerpt

OBJECTIVE: To ascertain whether other variations coexist with 1555(A--> G) mutation in the mitochondrial DNA and may aggravate the severity of hearing loss or increase the penetrance of 1555(A--> G) mutation in a large family with maternally inherited nonsyndromic deafness in Huaiyin, Jiangsu province. METHODS: PCR-restriction fragment length polymorphism (PCR-RFLP) was used to screen both the nt1555 and the...

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PMID: 16086269

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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