Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial tRNA(Ser(UCN)) variants in 2651 Han Chinese subjects with hearing loss.

Mitochondrion - 1 Jul 2015

Tang Xiaowen, Zheng Jing, Ying Zhengbiao, Cai Zhaoyang, Gao Yinglong, He Zheyun, Yu Han, Yao Juan, Yang Yaling, Wang Hui, Chen Ye, Guan Min-Xin

Abstract excerpt

Mutations in the mitochondrial DNA have been associated with hearing loss. However, the prevalence and spectrum of mitochondrial tRNA mutations in hearing-impaired subjects are poorly understood. In this report, we have investigated the prevalence and spectrum of mitochondrial tRNA(Ser(UCN)) mutations in a large cohort of 2651 Han Chinese subjects with hearing loss. The clinical evaluation showed that 744...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Gene Frequency

Share to Hearing Loss

Share to RNA, Transfer, Ser

Share to Young Adult

Source

Identifiers

PMID: 25968158
DOI: 10.1016/j.mito.2015.05.001

Genes

UCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial tRNA(Ser(UCN)) variants in 2651 Han Chinese subjects with hearing loss.PMID 25968158Read ↗

Maternally inherited hearing loss is associated with the novel mitochondrial tRNA Ser(UCN) 7505T>C mutation in a Han Chinese family.Semantic proximity Read ↗

Mitochondrial tRNA mutations in 887 Chinese subjects with hearing loss.Semantic proximity Read ↗

Low penetrance of hearing loss in two Chinese families carrying the mitochondrial tRNASer(UCN) mutations.Semantic proximity Read ↗

A novel mutation in the mitochondrial tRNA(Ser(UCN)) gene in a family with non-syndromic sensorineural hearing impairment.Semantic proximity Read ↗

The role of mitochondrial DNA mutations in hearing loss.Semantic proximity Read ↗

Mitochondrial tRNAGly A10055G mutation contributes to non-syndromic hearing loss: a study of three Han Chinese pedigrees.Semantic proximity Read ↗

Variants in mitochondrial tRNAGlu, tRNAArg, and tRNAThr may influence the phenotypic manifestation of deafness-associated 12S rRNA A1555G mutation in three Han Chinese families with hearing loss.Semantic proximity Read ↗

[Hearing loss and epilepsy may be associated with the novel mitochondrial tRNASer(UCN) 7472delC mutation in a Chinese family].Semantic proximity Read ↗

The mitochondrial tRNA(Ala) T5628C variant may have a modifying role in the phenotypic manifestation of the 12S rRNA C1494T mutation in a large Chinese family with hearing loss.Semantic proximity Read ↗

Nonsyndromic hearing loss caused by a mitochondrial T7511C mutation.Semantic proximity Read ↗

Coexistence of mitochondrial 12S rRNA C1494T and CO1/tRNA(Ser(UCN)) G7444A mutations in two Han Chinese pedigrees with aminoglycoside-induced and non-syndromic hearing loss.Semantic proximity Read ↗

The contribution of the mitochondrial COI/tRNA(Ser(UCN)) gene mutations to non-syndromic and aminoglycoside-induced hearing loss in Polish patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.