Article
Polymorphisms associated with the DAZ genes on the human Y chromosome.
Genomics - 1 Oct 2005
Lin Yi-Wen, Thi Duyen Anh Doan, Kuo Pao-Lin, Hsu Chao-Chin, Huang Bor-Ding, Yu Yueh-Hsiang, Vogt Peter H, Krause Walter, Ferlin Alberto, Foresta Carlo, Bienvenu Thierry, Schempp Werner, Yen Pauline H
Abstract excerpt
The human Y chromosome is unique in that it does not engage in pairing and crossing over during meiosis for most of its length. Y chromosome microdeletions, a frequent finding in infertile men, thus occur through intrachromosomal recombination, either within a single chromatid or between sister chromatids. A recently identified polymorphism associated with increased risk for spermatogenic failure, the gr/gr...
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