Article

Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene

1996-01-01

Abstract excerpt

We have detected deletions of portions of the Y chromosome long arm in 12 of 89 men with azoospermia (no spermatozoa in their semen). No Y deletions were detected in their male relatives or in 90 other fertile males. The 12 deletions overlap, defining a region likely to contain one or more genes required for spermatogenesis (the azoospermia factor, AZF). Deletion of the AZF region is associated with highly variabl...

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Literature Corpus work: 949014be-cd24-55bf-96c5-434157e014bb
DOI: 10.1093/humrep/11.suppl_4.27

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