Article

Isoform-Specific Functions of p73 Drive Survival and Chemoresistance in Diffuse Large B-Cell Lymphoma

2026-02-02

Abstract excerpt

Diffuse large B-cell lymphoma (DLBCL) represents 30–40% of non-Hodgkin lymphoma cases and is curable in >60% of patients; however, approximately one-third ultimately relapse. Although prior studies in normal B cells and lymphoma models implicate p73 in B-cell lymphomagenesis, the functional role of individual p73 isoforms in DLBCL remains poorly defined. TP73, a TP53 family member located on chromosome 1p36, encod...

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Literature Corpus work: 97cbb149-53c5-5771-9bbf-90385d2ad954
DOI: 10.64898/2026.01.28.702345

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