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Article

Quantitative protein expression analysis of CLL B cells from mutated and unmutated IgV(H) subgroups using acid-cleavable isotope-coded affinity tag reagents.

Journal of proteome research - 1 Jan 2000

Barnidge David R, Jelinek Diane F, Muddiman David C, Kay Neil E

Abstract excerpt

Relative protein expression levels were compared in leukemic B cells from two patients with chronic lymphocytic leukemia (CLL) having either mutated (M-CLL) or unmutated (UM-CLL) immunoglobulin variable heavy chain genes (IgV(H)). Cells were separated into cytosol and membrane protein fractions then labeled with acid-cleavable ICAT reagents (cICAT). Labeled proteins were digested with trypsin then subjected to...

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Share to Cell Fractionation
Share to Genes, Immunoglobulin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia, Lymphocytic, Chronic, B-Cell

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Source

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Identifiers

PMID: 16083281
DOI: 10.1021/pr050028f
PMCID: PMC1403294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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