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Article

Altered Cytokine Responses of Dengue-Specific CD4+ T Cells to Heterologous Serotypes

1 Aug 2005

Abstract excerpt

The interplay of different inflammatory cytokines induced during a dengue (DEN) virus infection plays a role in either protection or increased disease severity. We measured the frequencies and characterized the cytokine responses of DEN virus-specific memory CD4+ T cells in PBMC of six volunteers who received experimental live attenuated monovalent DEN vaccines. IFN-gamma and TNF-alpha responses to inactivated...

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PMID: 16081844
DOI: 10.4049/jimmunol.175.4.2676

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