Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Altered gene expression in myeloproliferative disorders correlates with activation of signaling by the V617F mutation of Jak2

5 Aug 2005

Abstract excerpt

We identified 13 new gene expression markers that were elevated and one marker, ANKRD15, that was down-regulated in patients with polycythemia vera (PV). These 14 markers, as well as the previously described PRV1 and NF-E2, exhibited the same gene expression alterations also in patients with exogenously activated granulocytes due to sepsis or granulocyte colony-stimulating factor (G-CSF) treatment. The recently...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Myeloid Leukemia Treatments
Share to Eosinophilic Disorders and Syndromes
Share to Myeloproliferative Neoplasms: Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16081684
DOI: 10.1182/blood-2005-05-1889

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Altered gene expression in myeloproliferative disorders correlates with activation of signaling by the V617F mutation of Jak2PMID 16081684Read ↗

Transcriptional profiling of polycythemia vera identifies gene expression patterns both dependent and independent from the action of JAK2V617F.Semantic proximity Read ↗

Gene expression profiling in polycythaemia vera: overexpression of transcription factor NF-E2.Semantic proximity Read ↗

Proinflammatory Cytokine IL-6 and JAK-STAT Signaling Pathway in Myeloproliferative Neoplasms.Semantic proximity Read ↗

Gene and microRNA analysis of neutrophils from patients with polycythemia vera and essential thrombocytosis: down-regulation of micro RNA-1 and -133aSemantic proximity Read ↗

Aberrant expression of microRNA in polycythemia vera.Semantic proximity Read ↗

Molecular profiling of peripheral blood cells from patients with polycythemia vera and related neoplasms: Identification of deregulated genes of significance for inflammation and immune surveillanceSemantic proximity Read ↗

Early and late stage MPN patients show distinct gene expression profiles in CD34+ cellsSemantic proximity Read ↗

Gene expression profiling distinguishes JAK2V617F-negative from JAK2V617F-positive patients in essential thrombocythemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.