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Article

Susceptibility genes for age-related maculopathy on chromosome 10q26.

American journal of human genetics - 1 Sept 2005

Jakobsdottir Johanna, Conley Yvette P, Weeks Daniel E, Mah Tammy S, Ferrell Robert E, Gorin Michael B

Abstract excerpt

On the basis of genomewide linkage studies of families affected with age-related maculopathy (ARM), we previously identified a significant linkage peak on 10q26, which has been independently replicated by several groups. We performed a focused SNP genotyping study of our families and an additional control cohort. We identified a strong association signal overlying three genes, PLEKHA1, LOC387715, and PRSS11. All...

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Share to Chromosomes, Human, Pair 10
Share to Genetic Linkage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intracellular Signaling Peptides and Proteins

Share to Linkage Disequilibrium

Share to Macular Degeneration

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Source

Open in PubMed Open full text

Identifiers

PMID: 16080115
DOI: 10.1086/444437
PMCID: PMC1226205

Genes

PLEKHA1
GRK5
RGS10

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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