Article
Investigation of autism and GABA receptor subunit genes in multiple ethnic groups.
Neurogenetics - 1 Jul 2006
Collins Ann L, Ma Deqiong, Whitehead Patrice L, Martin Eden R, Wright Harry H, Abramson Ruth K, Hussman John P, Haines Jonathan L, Cuccaro Michael L, Gilbert John R, Pericak-Vance Margaret A
Abstract excerpt
Autism is a neurodevelopmental disorder of complex genetics, characterized by impairment in social interaction and communication, as well as repetitive behavior. Multiple lines of evidence, including alterations in levels of GABA and GABA receptors in autistic patients, indicate that the GABAergic system, which is responsible for synaptic inhibition in the adult brain, may be involved in autism. Previous studies...
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