Replicative fitness in vivo of HIV-1 variants with multiple drug resistance-associated mutations.

doi:10.1002/jmv.2023

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Article

Replicative fitness in vivo of HIV-1 variants with multiple drug resistance-associated mutations.

Journal of medical virology - 1 Oct 2001

Devereux H L, Emery V C, Johnson M A, Loveday C

Abstract excerpt

The relative fitness of HIV-1 viral variants containing a broad range of drug resistance-associated mutations has been little studied in vivo. Understanding the relative fitness associated with viruses containing mutations may aid future therapeutic management. The aim of this study was to investigate the relative fitness of mutant viruses by assessing a cohort of patients who had developed resistance to many...

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PMID: 11536226
DOI: 10.1002/jmv.2023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.