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Article

Genetic interactions between polymorphisms that affect gene expression in yeast.

Nature - 4 Aug 2005

Brem Rachel B, Storey John D, Whittle Jacqueline, Kruglyak Leonid

Abstract excerpt

Interactions between polymorphisms at different quantitative trait loci (QTLs) are thought to contribute to the genetics of many traits, and can markedly affect the power of genetic studies to detect QTLs. Interacting loci have been identified in many organisms. However, the prevalence of interactions, and the nucleotide changes underlying them, are largely unknown. Here we search for naturally occurring genetic...

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Identifiers

PMID: 16079846
DOI: 10.1038/nature03865
PMCID: PMC1409747

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