Article
Characterization of cell lines derived from tumors induced by TC-1 cells in mice preimmunized against HPV16 E7 oncoprotein.
International journal of oncology - 1 Sept 2005
Smahel Michal, Smahelová Jana, Tejklová Pavla, Tachezy Ruth, Marinov Iuri
Abstract excerpt
Escape of tumor cells from the host immune system is probably the most difficult obstacle to overcome in attempts to enhance the efficacy of immunotherapy of tumors. To solve the problem, animal models with escape mechanisms found in human tumors are needed. We have already established cell lines...
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