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Article

Human papillomavirus-driven immune deviation: challenge and novel opportunity for immunotherapy

1 Jun 2017

Abstract excerpt

It is now recognized that the immune system can be a key component of restraint and control during the neoplastic process. Human papillomavirus (HPV)-associated cancers of the anogenital tract and oropharynx represent a significant clinical problem but there is a clear opportunity for immune targeting of the viral oncogene expression that drives cancer development. However, high-risk HPV infection of the target...

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PMID: 28794879
DOI: 10.1177/2051013617717914

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