Article
Altered monocytic phenotypes are linked with systemic inflammation and may be linked to mortality in dialysis patients.
Scientific reports - 13 Dec 2019
Brandt Sabine, Ewert Lara, Scurt Florian G, Reichardt Charlotte, Lindquist Jonathan A, Gorny Xenia, Isermann Berend, Mertens Peter R
Abstract excerpt
The major causes for increased morbidity and mortality among chronic kidney disease patients are cardiovascular diseases and infection. A causal link between an activated immune system and aggravated atherosclerosis has been postulated that skews the system towards inflammatory responses. Previously, we demonstrated a positive association of pro-inflammatory cytokines with monocytic Y-box binding protein-1 (YB-1)...
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