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Article

Apoptotic cell-free DNA promotes inflammation in haemodialysis patients

13 Dec 2011

Abstract excerpt

BACKGROUND: A proinflammatory environment characterized by the continuous activation of the innate immune system is thought to contribute to the markedly elevated mortality in haemodialysis (HD) patients with end-stage renal disease (ESRD). The presence of circulating cell-free DNA (cfDNA) has been demonstrated as biomarker in many pathologies. METHODS: We evaluated the occurrence of cfDNA in HD patients and its...

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PMID: 22167588
DOI: 10.1093/ndt/gfr695

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