Article
Interleukin-10 haplotype associated with total serum IgE in atopic dermatitis patients.
Allergy - 1 Sept 2005
Shin H D, Park B L, Kim L H, Kim J-S, Kim J-W
Abstract excerpt
BACKGROUND: The genetic background of atopic dermatitis (AD) is not clearly understood. Interleukin (IL)-10 is a powerful Th-2 cell cytokine produced by lymphoid cells that exerts its function by inhibiting macrophage/monocyte and T-cell lymphocyte replication and secretion of inflammatory cytokines [IL-1, tumour necrosis factor-alpha (TNFA), IL-6, IL-8 and IL-12]. OBJECTIVE: In an effort to discover additional...
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