Cytokine gene polymorphisms in atopic dermatitis.

doi:10.1046/j.1365-2133.2003.05307.x

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Article

Cytokine gene polymorphisms in atopic dermatitis.

The British journal of dermatology - 1 Jun 2003

Reich K, Westphal G, König I R, Mössner R, Schupp P, Gutgesell C, Hallier E, Ziegler A, Neumann C

Abstract excerpt

BACKGROUND: Atopic dermatitis (AD) and psoriasis are genetically determined inflammatory skin disorders characterized by abnormal cytokine production. From association studies there is evidence that functionally relevant cytokine gene polymorphisms contribute to the genetic basis of psoriasis. Association studies in AD have mostly been limited to polymorphisms of T-helper 2-type cytokines, which dominate in acute...

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PMID: 12828754
DOI: 10.1046/j.1365-2133.2003.05307.x

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