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Article

Distribution of caspase‐14 in epidermis and hair follicles is evolutionarily conserved among mammals

2 Sept 2005

Abstract excerpt

Caspase-14, a member of the caspase family of cysteine proteases, is almost exclusively expressed in the epidermis. Studies on human and mouse cells and tissues have implicated caspase-14 in terminal differentiation of epidermal keratinocytes and in the formation of the stratum corneum. Here we investigated evolutionary aspects of the role of caspase-14 by analyzing its distribution in the epidermis and hair...

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PMID: 16142807
DOI: 10.1002/ar.a.20234

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