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Article

Molecular basis of macrolide resistance in Campylobacter: role of efflux pumps and target mutations.

The Journal of antimicrobial chemotherapy - 1 Sept 2005

Mamelli Laurent, Prouzet-Mauléon Valérie, Pagès Jean-Marie, Mégraud Francis, Bolla Jean-Michel

Abstract excerpt

BACKGROUND: Erythromycin is the drug of choice to treat human campylobacteriosis. Campylobacter isolates exhibit two different phenotypes with regard to erythromycin resistance: high-level resistant strains (HLR) and low-level resistant strains (LLR). OBJECTIVES: To study the mechanisms of resistance of Campylobacter to erythromycin, its 6-O-methyl derivative clarithromycin and the ketolide telithromycin....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16055509
DOI: 10.1093/jac/dki253

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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