Article
Involvement of the CmeABC efflux pump in the macrolide resistance of Campylobacter coli.
The Journal of antimicrobial chemotherapy - 1 Nov 2005
Cagliero Cédric, Mouline Christian, Payot Sophie, Cloeckaert Axel
Abstract excerpt
OBJECTIVES: This study was conducted to examine the role of the CmeABC efflux pump in decreasing the susceptibility of Campylobacter coli to macrolides and ketolides in the context of absence or presence of mutations in the 23S rRNA genes. METHODS: The cmeB gene was inactivated in strains of C. coli showing two different patterns of erythromycin resistance (low or high level of resistance) associated with the...
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