Article
Relative contribution of target gene mutation and efflux to fluoroquinolone and erythromycin resistance, in French poultry and pig isolates of Campylobacter coli.
International journal of antimicrobial agents - 1 May 2004
Payot Sophie, Avrain Laetitia, Magras Catherine, Praud Karine, Cloeckaert Axel, Chaslus-Dancla Elisabeth
Abstract excerpt
Thirty-eight avian and swine French isolates of Campylobacter coli were studied for their mechanisms of co-resistance to fluoroquinolones and erythromycin. A Thr86Ile modification of GyrA, responsible for fluoroquinolone resistance, was found in all the strains. Two different levels of resistance to erythromycin (MIC of 8-16 or >/=256 mg/l) were observed. A A2075G mutation in the 23S rRNA genes was found only in...
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