Article
Genome-wide screens to identify genes of human pathogenic Yersinia species that are expressed during host infection.
Current issues in molecular biology - 1 Jul 2005
Darwin Andrew J
Abstract excerpt
An obvious goal in the study of bacteria that cause human disease is to identify the bacterial genes required for growth within the host. Historically, this has presented a significant technological challenge. However, with this goal in mind, the in vivo expression technology (IVET) and signature-tagged mutagenesis (STM) techniques were developed during the 1990s. These techniques have been used to identify...
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