Article
Distinct membrane effects of spinal nerve ligation on injured and adjacent dorsal root ganglion neurons in rats.
Anesthesiology - 1 Aug 2005
Sapunar Damir, Ljubkovic Marko, Lirk Philipp, McCallum J Bruce, Hogan Quinn H
Abstract excerpt
BACKGROUND: Painful peripheral nerve injury results in disordered sensory neuron function that contributes to the pathogenesis of neuropathic pain. However, the relative roles of neurons with transected axons versus intact adjacent neurons have not been resolved. An essential first step is identification of electrophysiologic changes in these two neuronal populations after partial nerve damage. METHODS: Twenty...
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