Article
Association between polymorphisms of the renin-angiotensin system and more severe histological forms of lupus nephritis.
Clinical nephrology - 1 Jul 2005
Sprovieri S R S, Sens Y A, Martini Filho D
Abstract excerpt
AIMS: The pathogenesis of lupus nephritis (LN) has not been fully understood. The renin-angiotensin system (RAS) is implicated in various immunological and non-immunological phenomena, and the polymorphism of the RAS genes has been associated with cardiovascular and renal disease onset and outcome. Therefore, we evaluated the possible association between the polymorphism of the renin-angiotensin system genes and...
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