Article
[Angiotensin-converting enzyme gene polymorphism and the clinical pathological features and progression in lupus nephritis].
Zhonghua nei ke za zhi - 1 Jul 1997
Guan T, Liu Z, Chen Z
Abstract excerpt
The renin-angiotensin system (RAS) is now well established as an important determinant in the progression of renal damage. The level of plasma angiotensin converting enzyme (ACE) is genetically determined and this gene effect is associated with insertion (I)/deletion (D) polymorphism in intron 16 of ACE gene. It has been reported that DD genotype of ACE gene is associated with a poor outcome in patients with IgA...
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