Article
Angiotensin II type 1 receptor gene polymorphism and serum angiotensin-converting enzyme level in Egyptian children with systemic lupus erythematosus.
Clinical rheumatology - 1 Dec 2018
Shoaib Rasha Mohamed Saleh, Hammad Ayman, Yahia Sohier, Elsaid Afaf, Abdel-Malak Camelia Adly
Abstract excerpt
Angiotensin II, the major effective molecule of the renin-angiotensin system, plays a vital role in the development of systemic lupus erythematosus (SLE). To study angiotensin II type 1 receptor (AT1R) gene polymorphism at (A1166C) in Egyptian children with SLE and its correlation with serum ACE level and SLE manifestations. AT1R gene polymorphism (A1166C) was done in 123 children with SLE in comparison to 100...
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