Article
Angiotensin-converting enzyme insertion/deletion gene polymorphism in Egyptian children with systemic lupus erythematosus: a possible relation to proliferative nephritis.
Lupus - 1 Jun 2017
Hammad A, Yahia S, Laimon W, Hamed S M, Shouma A, Shalaby N M, Abdel-Hady D, Ghanem R, El-Farahaty R M, El-Bassiony S R, Hammad E M
Abstract excerpt
Introduction Angiotensin-converting enzyme (ACE) is crucial in the pathogenesis of systemic lupus erythematosus through angiotensin II which regulates vascular tone and endothelial functions. Objectives To study the frequency of ACE insertion/deletion (I/D) gene polymorphism in Egyptian children with systemic lupus erythematosus and its possible relation to the renal pathology in cases with lupus nephritis....
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