Article
Molecular epidemiology of drug resistance markers of Plasmodium falciparum malaria in Thailand.
Tropical medicine & international health : TM & IH - 1 Aug 2005
Congpuong K, Na Bangchang K, Mungthin M, Bualombai P, Wernsdorfer W H
Abstract excerpt
To determine differences in the distribution of drug resistance mutations in the Plasmodium falciparum chloroquine resistance transporter (pfcrt) and P. falciparum multi-drug resistance 1 (pfmdr1) genes of P. falciparum isolates in Thailand, a study was conducted using polymerase chain reaction-r...
Topics
- ATP-Binding Cassette Transporters
- Animals
- Antimalarials
- Biomarkers
- Chloroquine
- Drug Resistance
- Endemic Diseases
- Genes, MDR
- Genotype
- Humans
- Malaria, Falciparum
- Mefloquine
- Membrane Proteins
- Membrane Transport Proteins
- Microbial Sensitivity Tests
- Mutation
- Plasmodium falciparum
- Polymorphism, Restriction Fragment Length