Article
Molecular characterization of Plasmodium falciparum antifolate resistance markers in Thailand between 2008 and 2016.
Malaria journal - 4 Mar 2020
Sugaram Rungniran, Suwannasin Kanokon, Kunasol Chanon, Mathema Vivek Bhakta, Day Nicholas P J, Sudathip Prayuth, Prempree Preecha, Dondorp Arjen M, Imwong Mallika
Abstract excerpt
BACKGROUND: Resistance to anti-malarials is a major threat to the control and elimination of malaria. Sulfadoxine-pyrimethamine (SP) anti-malarial treatment was used as a national policy for treatment of uncomplicated falciparum malaria in Thailand from 1973 to 1990. In order to determine whether withdrawal of this antifolate drug has led to restoration of SP sensitivity, the prevalence of genetic markers of SP...
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