Infectivity of Cryptosporidium hominis and Cryptosporidium parvum genotype 2 isolates in immunosuppressed Mongolian gerbils.

doi:10.1128/IAI.73.8.5252-5255.2005

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Article

Infectivity of Cryptosporidium hominis and Cryptosporidium parvum genotype 2 isolates in immunosuppressed Mongolian gerbils.

Infection and immunity - 1 Aug 2005

Baishanbo Asiya, Gargala Gilles, Delaunay Agnès, François Arnaud, Ballet Jean-Jacques, Favennec Loïc

Abstract excerpt

One-month-old dexamethasone-immunosuppressed Mongolian gerbils were challenged with 1 oocyst to 2 x 10(5) oocysts from two isolates genotyped as Cryptosporidium hominis and C. parvum (genotype 2), respectively. A similar dose-dependent gut infection was obtained, and the initial genotype maintained for 21 to 22 days. The data suggest that immunosuppressed gerbils provide a reliable rodent model of persistent C....

Topics

Animals
Cryptosporidiosis
Cryptosporidium parvum
Genotype
Gerbillinae
Immunosuppression Therapy

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Identifiers

PMID: 16041051
DOI: 10.1128/IAI.73.8.5252-5255.2005
PMCID: PMC1201256

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