Article
Development of patent infection in immunosuppressed C57Bl/6 mice with a single Cryptosporidium meleagridis oocyst.
The Journal of parasitology - 1 Jun 2003
Huang Kehe, Akiyoshi Donna E, Feng Xiaochuan, Tzipori Saul
Abstract excerpt
The ability of Cryptosporidium meleagridis to produce patent infection was studied in adult C57BL/6 mice that were immunosuppressed with dexamethasone phosphate provided in the drinking water at a dosage of 16 microg/ml. Four days after the onset of immunosuppression, mice were orally challenged with 1, 3, 10, or 1,000 C. meleagridis TU1867 oocysts per mouse. The mice were monitored daily for 18 days...
Topics
- Animals
- Cryptosporidiosis
- Cryptosporidium
- Disease Models, Animal
- Feces
- Female
- Genotype
- Immunocompromised Host
- Mice
- Mice, Inbred C57BL
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Random Allocation