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Differential levels of tissue hypoxia in the developing chicken heart

18 Jul 2005

Abstract excerpt

Tissue hypoxia plays a critical role in normal development, including cardiogenesis. Previously, we showed that oxygen concentration, as assessed by the hypoxia indicator EF5, is lowest in the outflow tract (OFT) myocardium of the developing chicken heart and may be regulating events in OFT morphogenesis. In this study, we identified additional areas of the embryonic chicken heart that were intensely positive for...

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PMID: 16028272
DOI: 10.1002/dvdy.20499

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