Article
Human SRCAP and Drosophila melanogaster DOM are homologs that function in the notch signaling pathway.
Molecular and cellular biology - 1 Aug 2005
Eissenberg Joel C, Wong Madeline, Chrivia John C
Abstract excerpt
The putative ATPase chromatin-remodeling machine SRCAP was identified in a yeast two-hybrid protein screen by interaction with the histone acetylase CBP. SRCAP is implicated in the transcriptional coactivation of cyclic AMP- and steroid-dependent promoters, but no natural chromosomal targets for SRCAP regulation have been identified. DOM is the unique SRCAP homolog in Drosophila melanogaster. The goal of this...
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