Article
SRC64 regulates the localization of a Tec-family kinase required for Drosophila ring canal growth.
Molecular cell - 1 May 1998
Guarnieri D J, Dodson G S, Simon M A
Abstract excerpt
Mutation of the Src64 gene of Drosophila results in ovarian ring canal defects and reduced female fertility. We used a dosage-sensitive modifier screen to search for downstream components of the SRC64 signaling pathway. We show that mutations affecting Tec29, an essential gene encoding a member of the Tec family of protein tyrosine kinases, dominantly enhance the Src64 ring canal phenotype. Loss of Tec29 function...
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