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Association of Oxidative Stress on Cognitive Function: A Bidirectional Mendelian Randomisation Study.

Molecular neurobiology - 1 Dec 2024

Fan Zhixing, Yang Chaojun, Qu Xiaoling, Zhang Jing, Wu Hui, Yang Ying, Huang Yifan, Zeng Ping, Xiang Zujin, Yang Jian

Abstract excerpt

The purpose of this study was to investigate the relationship between oxidative stress and cognitive function, encompassing cognitive performance, intelligence, memory, reaction time, speech and vision by a bidirectional Mendelian randomisation study. Independent genetic variants associated with glutathione S-transferase (GST), catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPX),...

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PMID: 38753129
DOI: 10.1007/s12035-024-04231-3

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