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Article

Ontogenetic development, differentiation, and phenotypic expression of macrophages in fetal rat lungs.

Journal of leukocyte biology - 1 May 1992

Higashi K, Naito M, Takeya M, Ando M, Araki S, Takahashi K

Abstract excerpt

Development, differentiation, and distribution of macrophages in fetal rat lungs were investigated immunohistochemically using anti-rat macrophage monoclonal antibodies. In the lung buds, RM-1+ macrophages were first detected on fetal day 13, and some showed reactivity for TRPM-2. They populated in the peribronchial mesenchyme of the lung buds, proliferated in loco, and showed no peroxidase activity in any...

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PMID: 1602238
DOI: 10.1002/jlb.51.5.444

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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