Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A new method for screening and isolation of hypersecretion mutants in Aspergillus niger.

Applied microbiology and biotechnology - 1 Feb 2006

Weenink Xavier O, Punt Peter J, van den Hondel Cees A M J J, Ram Arthur F J

Abstract excerpt

Although filamentous fungi have a unique property of secreting a large amount of homologous extracellular proteins, the use of filamentous fungi as hosts for the production of heterologous proteins is limited because of the low production levels that are generally reached. Here, we report a general screening method for the isolation of mutants with increased protein production levels. The screening method makes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aspergillus niger
Share to Biomass
Share to Glucan 1,4-alpha-Glucosidase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Laccase

Share to Pleurotus

Share to Protein Transport

Share to Recombinant Proteins

Share to Starch

Source

Identifiers

PMID: 16021486
DOI: 10.1007/s00253-005-0013-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A new method for screening and isolation of hypersecretion mutants in Aspergillus niger.PMID 16021486Read ↗

The F-box protein gene exo-1 is a target for reverse engineering enzyme hypersecretion in filamentous fungi.Semantic proximity Read ↗

Further enhanced production of heterologous proteins by double-gene disruption (ΔAosedD ΔAovps10) in a hyper-producing mutant of Aspergillus oryzae.Semantic proximity Read ↗

Branching mutants of Aspergillus oryzae with improved amylase and protease production on solid substrates.Semantic proximity Read ↗

Forward genetics screen coupled with whole-genome resequencing identifies novel gene targets for improving heterologous enzyme production in Aspergillus niger.Semantic proximity Read ↗

Direct Liquid-Culture Screening for Evaluating the Production of Heterologous Proteins Using an Auxotrophic Mutant of Aspergillus Oryzae.Semantic proximity Read ↗

Identification of a Classical Mutant in the Industrial Host Aspergillus niger by Systems Genetics: LaeA Is Required for Citric Acid Production and Regulates the Formation of Some Secondary Metabolites.Semantic proximity Read ↗

Differential proteomics reveals main determinants for the improved pectinase activity in UV-mutagenized Aspergillus niger strain.Semantic proximity Read ↗

New protease mutants in Aspergillus niger result in strongly reduced in vitro degradation of target proteins; genetical and biochemical characterization of seven complementation groups.Semantic proximity Read ↗

Hyperproduction of β-Glucanase Exg1 Promotes the Bioconversion of Mogrosides in Saccharomyces cerevisiae Mutants Defective in Mannoprotein Deposition.Semantic proximity Read ↗

Glucoamylase::green fluorescent protein fusions to monitor protein secretion in Aspergillus niger.Semantic proximity Read ↗

New multi-marker strains and complementing genes for Aspergillus nidulans molecular biology.Semantic proximity Read ↗

Altered secretion patterns and cell wall organization caused by loss of PodB function in the filamentous fungus Aspergillus nidulans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.